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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
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The Mesoscale K15598U-2 is a high-performance thermoelectric module for cooling or heating It measures 40 x 40 x 3 4mm with a heat pumping capacity of 15 5W Operating on 15V it achieves a temperature difference of 68 C using Bismuth Telluride-based alloys It has a no-load voltage of 2 7V internal resistance of 1 4 ohms and withstands temperatures from -40 C to 125 C A heat sink and fan are needed for optimal performance This robust module is ideal for precision temperature control
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The V-PLEX Plus Cytokine Panel 1 (Mouse) Kit from Meso Scale Discovery is a multiplex immunoassay that allows simultaneous measurement of 10 mouse cytokines and chemokines (GM-CSF IFN- IL-1 IL-2 IL-4 IL-5 IL-6 IL-10 IL-12p70 and TNF- ) from cell culture supernatants serum plasma and other biological fluids The kit utilizes electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The 10-plex panel allows efficient profiling of cytokines and chemokines involved in innate and adaptive immune responses
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The Mesoscale K15514U-2 is a high-performance thermoelectric cooler for photonics and semiconductor applications offering precise temperature control It has a 15W heat pumping capacity and a 70 C temperature differential With dimensions of 30 x 30 x 3 4mm it includes a thermistor for temperature sensing This Peltier cooler is ideal for stabilizing laser diodes and cooling sensors featuring a high coefficient of performance and low power consumption A heat sink and fan are required for heat dissipation from the hot side
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The V-PLEX SARS-CoV-2 Panel 32 IgG Kit from Meso Scale Diagnostics is an immunoassay that quantitatively measures IgG antibodies to SARS-CoV-2 in human serum and plasma This kit includes a 96-well plate coated with SARS-CoV-2 spike protein antigens detection antibodies calibrators controls diluent wash buffer read buffer and plate seals The electrochemiluminescence immunoassay takes approximately 3 5 hours to run and has a dynamic range of 50-100 000 U/mL This assay can aid in understanding IgG seroprevalence and immune response to SARS-CoV-2
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The Mesoscale K15637U-2 is a high-performance thermoelectric cooler for photonics and semiconductor applications offering precise temperature control It has a heat pumping capacity of 15 5W and a temperature differential of up to 70 C The multi-stage cascaded design with Bi2Te3 elements and integrated heat exchangers provides high cooling power in a compact 40 x 40 x 3 4mm size It requires a controlled current source and heat sink The K15637U-2 is ideal for applications needing precise temperature management in limited spaces
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The Meso Scale Discovery V-PLEX Human IL-6 Kit is a highly sensitive and quantitative immunoassay for the detection of human interleukin 6 (IL-6) in cell culture supernatants serum plasma and other biological fluids This kit utilizes electrochemiluminescence technology and provides accurate reproducible results in just 3 5 hours The kit includes a 96-well plate coated with capture antibody detection antibody conjugated to an electrochemiluminescent label calibrators diluent read buffer wash buffer and plate seals The assay has a sensitivity of 0 3 pg/mL and a broad dynamic range from 0 3-2500 pg/mL This kit allows for the rapid reliable quantification of IL-6 levels
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The V-PLEX Plus Human ProInflam Panel I 4-plex Kit from Meso Scale Discovery is a multiplex immunoassay measuring human IFN- IL-1 IL-6 and TNF- in serum plasma and culture supernatants This electrochemiluminescent assay uses MSD s SULFO-TAG labels and multi-array plate technology for sensitive reproducible results from small samples The 4-plex panel efficiently quantifies proinflammatory cytokines aiding immunology inflammation and drug discovery research The kit includes a 96-well plate detection antibodies read buffer calibrators and protocols for assay optimization and data analysis
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The Meso Scale Discovery V-PLEX Plus Viral Panel 2 Human Kit is a multiplex immunoassay that simultaneously detects antibodies to SARS-CoV-2 Influenza A Influenza B and RSV in human serum and plasma This assay kit includes a 96-well plate coated with antigens for the viruses detection antibodies assay buffers wash buffers calibrators and controls The electrochemiluminescence technology allows for high sensitivity and a broad dynamic range This kit can help track immune responses to viral infections and vaccines with results in just a few hours
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The Meso Scale Discovery K15645U-4 is a 96-well plate coated with a proprietary carbon electrode sensor that enables label-free detection of biomolecules It is designed for quantitative measurement of total tau protein in human CSF and plasma samples using electrochemiluminescence (ECL) detection This assay kit includes a 96-well plate tau detection antibody sample diluent calibrator diluent wash buffer read buffer and calibrators to generate a standard curve The ECL signal is proportional to the amount of tau protein present in the sample This assay has high sensitivity and a broad dynamic range to quantitate total tau levels
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The Meso Scale Discovery V-PLEX Cytokine Panel 1 (NHP) Kit is designed to simultaneously measure multiple monkey cytokines in serum plasma and culture supernatants This kit can quantitatively measure IL-1 IL-2 IL-4 IL-5 IL-6 IL-10 IL-12p70 IL-13 IL-17A IFN- and TNF- The electrochemiluminescent detection method provides high sensitivity up to 5-logs of dynamic range and low sample consumption This kit includes a 96-well plate coated with capture antibodies detection antibodies read buffer calibrator blend serum and plasma diluent wash buffer and adhesive plate seals sufficient for one 96-well plate
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The V-PLEX Plus Human ProInflam Panel I 4-plex is a multiplex immunoassay kit from Meso Scale Diagnostics for measuring 4 human proinflammatory biomarkers (IFN- IL-1 IL-6 TNF- ) in serum plasma and culture supernatants It uses electrochemiluminescence detection for high sensitivity and broad range with low sample volume The kit includes a 96-well plate with capture antibodies detection antibodies calibrators diluent wash buffer read buffer and plate seals enabling efficient analysis of inflammation biomarkers from a small sample
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The Meso Scale Discovery V-PLEX Plus Viral Panel 1 NHP Kit is a multiplex immunoassay that simultaneously detects antibodies to SARS-CoV-2 Influenza A Influenza B and RSV in non-human primate serum plasma and lung lavage samples This assay kit includes a 96-well plate detection antibodies wash buffers calibrators controls and other reagents needed to run the immunoassay on the MSD platform The V-PLEX Plus Viral Panel 1 NHP Kit allows for high-throughput quantitative antibody profiling of NHP samples enabling researchers to efficiently monitor immune responses to respiratory viruses in preclinical studies
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An alkaloid active against the F32 chloroquine-sensitive (IC50 0 52 UM) and FcB1 and FcM2 chloroquine-resistant strains of P falciparum (IC50s 0 52 0 8 and 0 49 UM respectively) and reduces parasitemia in a mouse model of P vinckei infection (ED50 18 9 mg/kg per day) decreases LPS-induced increases in TNF-a IL-1B and IL-6 levels and p65 nuclear translocation in RAW 264 7 cells at 5 UM decreases serum levels of IL-10 TNF-a and IL-6 and reduces mortality in a mouse model of LPS-induced endotoxemia inhibits proliferation of various cancer cells (IC50s 2 65-370 ng/ml) induces apoptosis and decreases STAT3 phosphorylation in HSC3 and HSC4 oral cancer cells from 0 1-10 UM and reduces tumor growth in an HSC3 mouse xenograft model at 10 mg/kg per day for 24 days
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The Mesoscale K15575U-4 is a high-performance thermoelectric cooler that provides precise temperature control for photonics and semiconductor applications It features a maximum heat pumping capacity of 15 5W and can achieve a temperature differential of up to 75 C With its compact 15 5mm x 15 5mm footprint the K15575U-4 TEC is designed for cooling small components and stabilizing sensitive devices This thermoelectric module utilizes bismuth telluride semiconductor material and incorporates a ceramic substrate for optimal thermal transfer The K15575U-4 requires a controlled DC power supply for operation
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The Mesoscale K15671U-2 is a high-performance thermoelectric cooler with a maximum heat pumping capacity of 15W It contains an array of 127 thermocouples and can achieve a maximum temperature differential of 70 C This Peltier cooler has a no load voltage of 15 4V and can handle up to 10A of current With dimensions of 40 x 40 x 3 4mm this small thermoelectric module can be used for a variety of precision temperature control and cooling applications The K15671U-2 has a thermal resistance of 0 6K/W and is designed for reliable maintenance-free operation
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